Exelon
Brand
name:Exelon
Pronounced: ECKS-ell-on
Generic name: Rivastigmine tartrate
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Why
is Exelon prescribed?
Exelon
is used in the treatment of mild to moderate Alzheimer's disease.
Alzheimer's disease causes physical changes in the brain that
disrupt the flow of information and interfere with memory, thinking,
and behavior. By boosting levels of the chemical messenger acetylcholine,
Rivastigmine tartrate can temporarily improve brain function in
some Alzheimer's sufferers, though it does not halt the progress
of the underlying disease. Exelon may become less effective as
the disease progresses.
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Most
important fact about Exelon
Patience
is in order when starting Rivastigmine tartrate. It can take up
to 12 weeks before Exelon's full benefits appear.
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How
should you take Exelon?
Exelon
should be taken with food in the morning and in the evening.
--If
you miss a dose...
Give
the forgotten dose as soon as you remember. If it is almost time
for the next dose, skip the one you missed and go back to the
regular schedule. Never double the dose.
--Storage
instructions...
Store
at room temperature in a tightly closed container.
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What
side effects may occur?
Side
effects from Rivastigmine tartrate cannot be anticipated. If any
side effects develop or change in intensity, inform your doctor
as soon as possible. Only your doctor can determine if it is safe
to continue taking Exelon.
More common side effects may include:
Abdominal pain, accidental injury, anxiety, aggression, confusion,
constipation, depression, diarrhea, dizziness, drowsiness, fainting,
fatigue, flu-like symptoms, gas, hallucinations, headache, high
blood pressure, increased sweating, indigestion, inflamed nasal
passages, insomnia, loss of appetite, nausea, tremor, unwell feeling,
urinary infection, vomiting, weakness, weight loss
Less
common side effects may include:
Belching
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Why
should Exelon not be prescribed?
Exelon
cannot be used if it causes an allergic reaction.
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Special
warnings about Exelon
Exelon
often causes nausea and vomiting, especially at the beginning
of treatment. The problem is more likely in women, but it can
lead to significant weight loss in both women and men. Tell your
doctor immediately if these side effects occur.
The
chance of severe vomiting increases when Rivastigmine tartrate
is given after an interruption of several days. Do not start giving
the drug again without first checking with the doctor. Dosage
may need to be reduced to the lowest starting level.
Exelon
may aggravate asthma and other breathing problems and can increase
the risk of seizures. Other drugs of its type are also known to
increase the chance of ulcers, stomach bleeding, and urinary obstruction,
although these problems have not been noted with Rivastigmine
tartrate. Drugs in this category can also slow the heartbeat,
possibly causing fainting in people who have a heart condition.
Contact your doctor if any of these problems occur.
Exelon
has not been tested in children.
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Possible
food and drug interactions
If Exelon is taken with certain other drugs, the effects of either
could be increased, decreased, or altered. It is especially important
to check with your doctor before combining Exelon with the following:
Bethanechol
(Urecholine)
Drugs that control spasms, such as Bentyl, Donnatal, and Levsin.
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Special
information
Exelon is not intended for women of child-bearing age, and its
effects during pregnancy and breastfeeding have not been studied.
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Recommended
dosage
ADULTS
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The usual starting dose is 1.5 milligrams 2 times a day for at
least 2 weeks. At 2 week intervals, the doctor may then increase
the dose to 3 milligrams, 4.5 milligrams, and finally 6.0 milligrams
2 times a day. Higher doses tend to be more effective. The maximum
dosage is 12 milligrams daily.
If side effects such as nausea and vomiting begin to develop,
the doctor may recommend skipping a few doses, then starting again
at the same or the next lowest dosage.
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Overdosage
Any
medication taken in excess can have serious consequences. If you
suspect an overdose, seek emergency medical attention immediately.
Symptoms
of Rivastigmine tartrate overdose may include:
Collapse, convulsions, breathing difficulty, extreme muscle weakness
(possibly ending in death if breathing muscles are affected),
low blood pressure, salivation, severe nausea, slow heartbeat,
sweating, vomiting
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