Augmentin

Brand name:Augmentin
Pronounced: awg-MENT-in
Generic name: Amoxicillin, Clavulanate potassium

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Why is Augmentin prescribed?

Augmentin is used in the treatment of lower respiratory, middle ear, sinus, skin, and urinary tract infections that are caused by certain specific bacteria. These bacteria produce a chemical enzyme called beta lactamase that makes some infections particularly difficult to treat.

Augmentin ES-600, a stronger, oral-suspension form of the drug, is prescribed for certain stubborn ear infections that previous treatment has failed to clear up in children two and under, or those attending day care.

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Most important fact about Augmentin

If you are allergic to either penicillin or cephalosporin antibiotics in any form, consult your doctor before taking Augmentin. You may be allergic to it, and if a reaction occurs, it could be extremely severe. If you take the drug and feel signs of a reaction, seek medical attention immediately.

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How should you take Augmentin?

Augmentin should be taken every 8 or 12 hours, depending on the dosage strength. It may be taken with or without food, but taking it with meals or snacks will help prevent stomach upset. Be sure to take all the medicine your doctor has prescribed, even if you begin to feel better.

Shake the suspension well. Use a dosing spoon or medicine dropper to give a child the medication; rinse the spoon or dropper after each use.

—If you miss a dose…

Take it as soon as you remember. If it is almost time for the next dose, and you take 2 doses a day, take the one you missed and the next dose 5 to 6 hours later. If you take 3 doses a day, take the one you missed and the next dose 2 to 4 hours later. Then go back to your regular schedule.

—Storage instructions…

Store the suspension under refrigeration and discard after 10 days. Store tablets away from heat, light, and moisture.

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What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Augmentin.

More common side effects may include:
Diarrhea/loose stools, nausea, skin rashes and hives

Less common side effects may include:
Abdominal discomfort, anemia, arthritis, black "hairy" tongue, blood disorders, fever, gas, headache, indigestion, intestinal inflammation, itching, itching or burning of the vagina, joint pain, muscle pain, skin inflammation, skin peeling, sores and inflammation in the mouth and on the tongue and gums, stomach inflammation, vomiting, yeast infection

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Rare side effects may include:
Agitation, anxiety, behavioral changes, blood in the urine, change in liver function, confusion, convulsions, dizziness, hyperactivity, insomnia, kidney problems

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Why should Augmentin not be prescribed?

If you are sensitive to or have ever had an allergic reaction to any penicillin medication, do not take this drug.

Also avoid taking Augmentin if it has ever given you liver problems or yellowing of the skin and eyes.

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Special warnings about Augmentin

Augmentin and other penicillin-like medicines are generally safe; however, anyone with liver, kidney, or blood disorders is at increased risk when using this drug. Alternative choices may be available to your doctor.

If you have diabetes and test your urine for the presence of sugar, you should ask your doctor or pharmacist if this medication will interfere with the type of test you use.

Allergic reactions to this medication can be serious and possibly fatal. Let your doctor know about previous allergic reactions to medicines, food, or other substances before using Augmentin. If you experience a reaction, report it to your doctor immediately and seek medical treatment.

If you develop diarrhea while taking Augmentin, inform your doctor. It could be a sign of a potentially dangerous form of bowel inflammation.

Some formulations of Augmentin contain phenylalanine. If you have the hereditary disease phenylketonuria, check with your doctor or pharmacist before taking this drug.

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Possible food and drug interactions
Augmentin may react with the antigout medication Benemid, resulting in changes in blood levels. A reaction with another antigout drug, Zyloprim, may cause a rash. Notify your doctor if you are taking either of these drugs.

Like many antibiotics, Augmentin may reduce the effectiveness of birth control pills. You may want to take additional measures while taking Augmentin.

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Special information
The effects of Augmentin during pregnancy have not been adequately studied. Because there may be risk to the developing baby, doctors usually recommend Augmentin to pregnant women only when the benefits of therapy outweigh any potential danger. Augmentin appears in breast milk and could affect a nursing infant. If Augmentin is essential to your health, your doctor may advise you to stop nursing your baby until your treatment with this drug is finished.

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Recommended dosage

ADULTS

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The usual adult dose is one 500-milligram tablet every 12 hours or one 250-milligram tablet every 8 hours. For more severe infections and infections of the respiratory tract, the dose should be one 875-milligram tablet every 12 hours or one 500-milligram tablet every 8 hours. It is essential that you take this medicine according to your doctor's directions.

CHILDREN LESS THAN 3 MONTHS OLD

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Children in this age group take 30 milligrams per 2.2 pounds of body weight per day, divided into 2 doses and taken every 12 hours.

CHILDREN OLDER THAN 3 MONTHS

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For middle ear infections, sinus inflammation, lower respiratory tract infections, and more severe infections, the usual dose of the 200- or 400-milligram suspension is 45 milligrams per 2.2 pounds per day, in 2 doses, every 12 hours, and of the 125- or 250-milligram suspension, 40 milligrams per 2.2 pounds per day, in 3 doses, every 8 hours.
For less severe infections, the usual dose is 25 milligrams of the 200- or 400-milligram suspension for each 2.2 pounds of weight per day, divided into 2 doses, every 12 hours, or 20 milligrams of the 125- or 250-milligram suspension per 2.2 pounds per day, divided into 3 doses, every 8 hours.

The usual dosage of Augmentin ES-600 oral suspension is 90 milligrams per 2.2 pounds of body weight per day, divided into 2 doses taken every 12 hours. Treatment lasts 10 days.

Children weighing 88 pounds or more will take the adult dosage of standard Augmentin.

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Overdosage

Augmentin is generally safe; however, large amounts may cause overdose symptoms. Suspected overdoses of Augmentin must be treated immediately; contact your physician or an emergency room.

Symptoms of Augmentin overdose may include:
Diarrhea, drowsiness, kidney problems, overactivity, rash, stomach and abdominal pain, vomiting