Avelox
Pronounced:
AV-eh-locks
Generic name: Moxifloxacin hydrochloride
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Why
is Avelox prescribed?
Avelox,
an antibiotic, is prescribed to treat sinus and lung infections.
It kills bacteria that can cause sinusitis, pneumonia, and secondary
infections in chronic bronchitis. It also fights skin infections
caused by staph or strep.
Avelox
is a member of the quinolone family of antibiotics. Like all antibiotics,
Avelox works only against bacteria. It will not cure an infection
caused by a virus.
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Most
important fact about Avelox
In
rare cases, antibiotics can cause a serious allergic reaction. Stop
taking Avelox and call your doctor immediately if you develop any
of the following warning signs: skin rash, tingling, hives, shortness
of breath, swelling of the face or throat, or difficulty swallowing.
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How
should you take Avelox?
Avelox
may be taken with or without food. Even if you feel better, finish
taking all the medicine that has been prescribed for you. If you
stop taking the drug too soon, surviving bacteria could cause a
relapse.
Be
sure to drink plenty of fluids while taking Avelox.
--If
you miss a dose...
Take
it as soon as you remember. If it is almost time for your next dose,
skip the one you missed and go back to your regular schedule. Do
not take a double dose in an effort to "catch up."
--Storage
instructions...
Store
Avelox at room temperature. Avoid high humidity.
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What
side effects may occur?
Most
people taking Avelox do not experience side effects; and when reactions
do occur, they are usually mild. If you do develop a side effect,
however, inform your doctor as soon as possible. Only your doctor
can determine if it is safe for you to continue taking Avelox.
- More
common side effects may include:
Nausea, diarrhea, dizziness
- Less
common side effects may include:
Abdominal pain, indigestion, headache, abnormal taste, vomiting
- Rare
side effects may include:
Allergic reaction (occasionally severe), anxiety, appetite loss,
bladder infection, blood clotting changes, back pain, body pain,
breathing difficulties, chest pain, chills, confusion, constipation,
cough, digestive system disorders, dim vision, drowsiness, dry
mouth, dry skin, fungal infections, gassiness, hallucinations,
hand pain, high blood pressure, high blood sugar, incoordination,
increased cough, insomnia, irregular heartbeat, itching, joint
pain, labored breathing, leg pain, low blood pressure, mouth sores,
nasal inflammation, nervousness, personality changes, pneumonia,
rapid heartbeat, rash, sinus inflammation, sore throat, stomach
irritation, sweating, swelling, tingling or burning sensations,
tongue inflammation, tremors, urinary inflammation, vaginal inflammation,
vague feeling of illness, vertigo, weakness, yellow eyes and skin
A
variety of other extremely rare side effects have been reported.
Check with your doctor if any new or unusual symptoms develop.
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Why
should Avelox not be prescribed?
If
you have ever had an allergic reaction to any other quinolone antibiotic,
such as Cipro, Floxin, Levaquin, Maxaquin, Noroxin, or Penetrex,
you should not take Avelox.
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Special
warnings about Avelox
Avelox
may make you dizzy or light-headed. Do not drive a car, operate
machinery, or engage in activities requiring mental alertness or
coordination until you know how the drug affects you.
Avelox
can cause certain heart irregularities in people already prone to
the problem. If you are being treated for an abnormal heartbeat,
make sure the doctor is aware of it. You may have to avoid Avelox.
Also tell the doctor if you or anyone in your family has a history
of heart problems. If you develop palpitations or fainting spells
while taking Avelox, contact your doctor immediately.
Before
you take Avelox, you should tell your doctor if you have a history
of convulsions or blockage of the arteries in the brain. Quinolone-type
antibiotics like Avelox have been known to cause convulsions and
other problems with the nervous system, including symptoms such
as agitation, anxiety, dizziness, confusion, depression, hallucinations,
nervousness, nightmares, tremors, and suicidal thoughts. Contact
your doctor immediately if you experience any of these reactions.
This
type of medication also may cause Achilles and other tendon ruptures,
especially in older adults and those taking steroids. If you experience
pain or inflammation in a tendon contact your doctor. Like other
antibiotics, it can also cause serious intestinal inflammation.
If you develop diarrhea, let your doctor know immediately.
Avelox
can make your skin more sensitive to light, so you should avoid
excess sunlight and tanning beds.
You
should avoid Avelox if you have a low level of potassium in your
blood. Low potassium can be caused by the water pills (diuretics)
often prescribed for high blood pressure. If you are taking a diuretic,
make sure the doctor knows about it before you begin treatment with
Avelox.
A
case of diarrhea during Avelox therapy could signal development
of a potentially dangerous bowel inflammation. Call your doctor
for treatment at the first sign of a problem.
Avelox
has not been tested in children under 18.
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Possible
food and drug interactions when taking Avelox
Multivitamins
containing iron or zinc; antacids containing magnesium, calcium,
or aluminum; Carafate (sucralfate); or Videx (didanosine) reduce
the effectiveness of Avelox. Take it at least 4 hours before or
8 hours after any of these products.
Do
not take Avelox with nonsteroidal anti-inflammatory drugs (NSAIDs)
such as Advil, Motrin, and Naprosyn because it may increase the
risk of nerve stimulation and convulsions.
Other
drugs to use cautiously while taking Avelox include:
Amiodarone (Cordarone)
Antipsychotic drugs such as Haldol, Stelazine, and Thorazine
Erythromycin (E-Mycin, Erythrocin)
Procainamide (Procan SR)
Quinidine (Quinidex)
Sotalol (Betapace)
Tricyclic antidepressants such as Elavil, Norpramin, and Triavil
Warfarin (Coumadin)
You
also should avoid Avelox if the amount of potassium in your blood
is low. Low potassium can sometimes be caused by diuretic medications
such as Lasix. If you are taking a diuretic medicine, tell your
doctor before taking Avelox. In fact, inform your doctor of all
medications you are taking, including over-the-counter remedies.
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Special
information
if you are pregnant or breastfeeding
The
effects of Avelox during pregnancy have not been studied. It should
be used during pregnancy only if the benefits outweigh the possible
risk to the unborn baby. If you are expecting, make sure the doctor
is aware of it before you start taking this drug.
Avelox
may appear in breast milk and could affect a nursing infant. If
this medication is essential to your health, your doctor may advise
you to discontinue breastfeeding until your treatment is finished.
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Recommended
dosage
ADULTS
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Acute
Bacterial Sinusitis
The
usual dose is one 400-milligram tablet daily for 7 to 14 days.
Acute
Bacterial Infection with Chronic Bronchitis
The
usual dose is one 400-milligram tablet daily for 5 days.
Pneumonia
The
usual dose is one 400-milligram tablet daily for 7 to 14 days.
Skin
Infections
The
usual dose is one 400-milligram tablet daily for 7 days.
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Overdosage
Any
medication taken in excess can have serious consequences. If you
suspect an overdose, seek medical attention immediately.
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